I presented my review of the year in translational bioinformatics at the AMIA Summit on Translational Bioinformatics. It is highly biased and subject to all the problems of one person trying to do something like this, but I have made a PDF of the slides available here. These are papers published since January 2009 to present. I apologize for important papers that I have missed, and thanks to those who provided advice. As I have mentioned previously, you can also see the 2008 version and the 2009 version.