Friends,
I have agreed once again to give a talk at the AMIA Summit on Translational Bioinformatics ) on the “year in review” highlighting some of the most important papers in our field of translational bioinformatics. Last year’s talk is online.
I am writing to request that you nominate papers that you think are important for me to include from the last 12-15 months. Nominations of your own papers are fine, but much less compelling than nominations of others’ papers (you can collude though…). Here are the criteria:
- I define translational bioinformatics broadly, but expect it to involve molecular-level (genes, small molecules) data AND clinical-level data (diseases, symptoms, drugs)
- I define bioinformatics as the creation and application of novel methods of analysis/discovery
I have been trolling the sites myself, but want to make sure I ask colleagues in bioinformatics for their thoughts.
I would like to highlight papers that have done a good, creative job at the above, and have a chance to become “classics” over the next 10-20 years. I expect to discuss about ~15 papers in “1-2 slide” detail and then to have another list of 10 “noteworthy but not discussed in detail” papers.
I would like these nominations by 5 PM on 3/11. Thanks for your help. If you don’t want to post publically, you can send to me by email at russ.altman-at-stanford.edu.
4 responses so far ↓
Abhishek Tiwari // March 2, 2009 at 6:59 am
Addressing informatics challenges in Translational Research with workflow technology by Beaulah et al. can be a good article for your consideration
http://dx.doi.org/10.1016/j.drudis.2008.06.005
Michael Kuhn // March 2, 2009 at 7:22 am
A self-nomination, but from Science nonetheless: Campillos et al., Drug Target Identification Using Side-Effect Similarity
http://www.sciencemag.org/cgi/content/full/321/5886/263
Iddo Friedberg // March 2, 2009 at 4:23 pm
Most things from Jeff Gordon’s lab at WashU that have to do with the human gut flora & obesity.
This is a classic, but may be a bit old for your span:
http://bytesizebio.net/index.php/2009/01/25/every-man-an-island-pt-1/
This is newer:
http://bytesizebio.net/index.php/2009/01/26/every-man-an-island-pt-2/
OK, yeah, I shamelessly plugged my own blog here. Nevertheless, these are relevant.
Neil Macpherson // March 9, 2009 at 2:43 pm
I would recommend two papers that use bioinformatics to suggest improvements in cancer diagnosis and cancer prognosis.
http://www.biomedcentral.com/1755-8794/1/57
Discovery of DNA methylation markers in cervical cancer using relaxation ranking by Ongenaert et al. BMC Medical Genomics 1:57
http://www.biomedcentral.com/1741-7015/6/26
Genomic variation in myeloma: design, content, and initial application of the Bank On A Cure SNP Panel to detect associations with progression-free survival
Van Ness et al. BMC Medicine 1:57
The second paper has an associated commentary
http://www.biomedcentral.com/1741-7015/6/27
Although these are not self-cites, I do work for the publisher.